Search results for " mild asthma"

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Effects of Omalizumab Treatment in Patients With Recalcitrant Nasal Polyposis and Mild Asthma: A Multicenter Retrospective Study

2021

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a clinical entity with specific features that impacts significantly on patient quality of life (QoL). CRSwNP is often associated with asthma and is difficult to control and manage despite pharmacological and/or surgical treatment. Omalizumab, a monoclonal anti-IgE antibody, has emerged as a putative therapeutic option. Objective To evaluate the effects of omalizumab on nasal polyp (NP) size and QoL assessed by Sino-Nasal Outcome Test-22 (SNOT-22) in patients with recalcitrant CRSwNP and mild asthma. Methods A multicenter retrospective analysis of patient data from the Community of Valencia (Spain) was performed. Adult patients …

Adultmedicine.medical_specialtyMild asthmaOmalizumabOmalizumabaspirin-exacerbated respiratory diseasechronic rhinosinusitis with nasal polypsImmunoglobulin E03 medical and health sciencesNasal Polyps0302 clinical medicineQuality of lifeSNOT-22Internal medicinemedicineHumansImmunology and AllergyNasal polypsIn patient030223 otorhinolaryngologyRetrospective StudiesRhinitisnasal polypsbiologybusiness.industrytotal nasal endoscopic polyp scoreRetrospective cohort studyGeneral Medicinemedicine.diseaseAsthmaTreatment Outcomequality of lifetissue eosinophilia030228 respiratory systemOtorhinolaryngologyIgE SNOT-22 aspirin-exacerbated respiratory disease chronic rhinosinusitis with nasal polyps mild asthma nasal polyps omalizumab quality of life tissue eosinophilia total nasal endoscopic polyp scoreChronic DiseaseQuality of Lifebiology.proteinomalizumabAspirin exacerbated respiratory diseaseIgEbusinessmild asthmamedicine.drugAmerican Journal of Rhinology & Allergy
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The characteristics of different diagnostic tests in adult mild asthmatic patients: Comparison with patients with asthma-like symptoms by gastro-oeso…

2007

SummaryBackgroundDiagnosing asthma cannot be always easy. It is important to consider the validity of the diagnostic tests, and/or how much more commonly they are positive in patients with asthma compared to healthy subjects and, particularly, to patients with asthma-like symptoms.ObjectiveTo evaluate the validity of diagnostic tests for asthma, in terms of sensitivity, specificity, positive and negative predictive values, in patients with bronchial asthma compared to patients affected by gastro-oesophageal reflux disease (GERD) with asthma-like symptoms, and healthy control subjects without asthma and gastro-oesophageal reflux (GER).DesignSingle-center, cross-sectional, observational study…

MaleVital capacitySettore MED/09 - Medicina Internaadult mild asthmatic patientVital CapacityGastroenterologygastro-oesophageal reflux.Bronchoconstrictor AgentsLeukocyte CountSensitivityimmune system diseasesForced Expiratory VolumeMethacholine ChlorideEosinophil cationic proteinRespiratory diseaseMiddle Agedrespiratory systemmedicine.anatomical_structureDiagnostic testsGastroesophageal RefluxSpecificityFemalemedicine.drugcirculatory and respiratory physiologyAdultPulmonary and Respiratory Medicinemedicine.medical_specialtyBronchial Provocation TestsDiagnosis DifferentialFEV1/FVC ratioGastro-oesophageal reflux diseaseInternal medicinemedicineHumansAsthmabusiness.industryEosinophil Cationic ProteinSputumadult mild asthmatic patients; gastro-oesophageal reflux.Eosinophilmedicine.diseaseAsthmaSurgeryrespiratory tract diseasesEosinophilsSpirometryGERDMethacholineEpidemiologic MethodsbusinessBiomarkersGastro-oesophageal refluxRespiratory Medicine
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